"Harmine showed cytotoxicity against HL60 and K562 cell lines. Content is available under CC BY-SA 3.0 unless otherwise noted. Beta-carboline MAO inhibitors, such as harmine, bind with DNA and also exhibit anti-tumor properties. The c-myb proto-oncogene has been implicated in leukemogenesis, but possible mechanisms remain ill defined. Neuromedin U: a Myb-regulated autocrine growth factor for human myeloid leukemias. To gain further insight to this process, we used transcript profiling in K562 cells expressing a dominant-negative Myb (MERT) protein. Contact with K562 cells, a cell line derived from a pa tient with myeloid blast crisis of chronic myelogenous leukemia and bearing the BCR-ABL1translocation, is known to in-duce modest proliferations of NK cells [28, 32], and aug-ment NK cell proliferation in response to IL-15 [24]. بیعی(به انگلیسی: Natural killer cell) (NK cells) لنفوسیتهایی از دستگاه ایمنی بدن هستند که در ایمنی سلولی و ایمنی ذاتی (Innate immune system) دخیل هستند. This retrieves 19 … We genetically modified K562 cells to express two NK stimu- Harmine has been shown to bind one hundred times more effectively than its close analogue harmaline. ŸFLAG標定的hZIP1位在許多皮質細胞的內質網上，包括了Caco-2，更近一步透過在PC-3前列腺細胞操作hZIP1抗體可以更精確的證明這件事。 其他可能存在的Zinc transporter The Data Explorer tab enable to retrieve all the K562 cells sub-cellular and sub-nuclear short RNA fractions from ENCODE. Basic leucine zipper transcription factor, ATF-like 2 is a protein that, in humans, is encoded by the BATF2 gene. Like all cancer cell lines, it is immortal and can divide indefinitely.A unique aspect of the KBM-7 cell line is that it is near-haploid, meaning it contains only one copy for most of its chromosomes.Human chromosomes are typically diploid, meaning that there are two copies of … Midkine (MK or MDK), also known as neurite growth-promoting factor 2 (NEGF2), is a protein that in humans is encoded by the MDK gene. Media in category "K562 cells" The following 7 files are in this category, out of 7 total. This could explain the cytotoxic effect of Peganum harmala on these cells." b. G-protein coupled receptor 31 also known as 12-(S)-HETE receptor is a protein that in humans is encoded by the GPR31 gene.The human gene is located on chromosome 6q27 and encodes a G-protein coupled receptor protein composed of 319 amino acids. A total of 105 potential Myb gene … KBM-7 cells are a chronic myelogenous leukemia (CML) cell line used for biomedical research. This locus in K562 cells is most likely triploid. Fraction of reads containing each of the two alleles of SNP rs1053036 in NR_125431 in K562 genomic DNA (left) and K562 RNA-seq reads (right). The cells express elevated levels of p53 protein. این سلول‌ها جزء دستگاه ایمنی ذاتی بدن هستند. There is a G -> A mutation in codon 273 of the p53 gene resulting in an Arg -> His substitution and a C -> T mutation in codon 309 resulting in a Pro -> Ser substitution. The cells are positive for keratin by immunoperoxidase staining. We first select the "Expression experiments" sub-tab and search for wgEncodeCshlShortRnaSeqK562. Sensitivity of K562 and HL-60 Cells to Edelfosine, an Ether Lipid Drug, Correlates with Production of Reactive Oxygen Species ; Last edited on 17 September 2020, at 05:54. Retrieving K562 cells sub-cellular and sub-nuclear short RNA fractions from ENCODE DEX based datasource selection.

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